Intira Koodkaew, Khwanruedee Chaiyawan and Pimchanok Satapoomin

DOI: 10.14456/sjst-psu.2021.195

pp. 1499 - 1506

Abstract

The use of natural products to inhibit α-amylase and α-glucosidase is a strategy in the treatment of diabetes. This study
investigated the phytochemical profile and antioxidant activity of, and α-amylase and α-glucosidase inhibition by banana central
pseudo-stem juice (BPJ) from four cultivars [Kluai Hom Thong (KHT), Kluai Hak Muk (KHM), Kluai Namwa (KNW), and
Kluai Namwa Dam (KND)], and two parts (basal and distal), at two ages (3 and 5 months). The phytochemical content and
antioxidant activity in each part of BPJ were age-dependent. KND had the most polyphenol, while KHT had the most flavonoid,
ascorbic acid, and highest antioxidant activity. The basal part of the five month-old KHM tends to have the most potential for
treating diabetes because it has a high level of α-amylase (52.89±2.65%) inhibition and the strongest α-glucosidase inhibition
(66.91±2.26%) among the investigated samples. This information may be used as the starting point for the development of BPJderived products.

Keywords

• α-amylase inhibitor
• cultivars
• α-glucosidase inhibitor
• Musa