Original Article | 2003, Vol.25, No.2, pp. 239-243
HIV-1 protease inhibitory effects of medicinal plants used as self medication by AIDS patients
Supinya Tewtrakul, Sanan Subhadhirasakul and Sopa Kummee
pp. 239 - 243
Abstract
Thirty-six chloroform-, methanol-, and water- extracts of some plants used as self mediciation by AIDS patients were investigated for their HIV-1 protease (HIV-1 PR) inhibitory activities. Of these extracts, Boesenbergia pandurata (rhizome, chloroform extract) showed the most potent inhibitory activity against HIV-1 PR, followed by Boesenbergia pandurata (rhizome, MeOH extract) and Alpinia galanga (rhizome, MeOH extract) with the inhibitions of 64.92, 51.92 and 48.70%, respectively, at concentration of 100 µg/ml.
