Supinya Tewtrakul, Sanan Subhadhirasakul, Jindaporn Puripattanavong and Tassanee Panphadung

pp. 503 - 508

Abstract

Four flavonoids (pinostrobin, pinocembrin, cardamonin and alpinetin) isolated from the ethanol
extract of Boesenbergia pandurata Holtt. (yellow rhizome) were tested for their activities against HIV-1 protease (HIV-PR). The result showed that cardamonin exhibited an appreciable anti-HIV-1 PR activity with
an IC₅₀ value of 31 µg/ml.

Keywords

• HIV-1 protease
• inhibitory substance
• Boesenbergia pandurata