Original Article | 2006, Vol.28, No.6, pp. 1209-1215
Syntheses of (±)-Romucosine and (±)-Cathafiline
Surachai Nimgirawath, Surachai Nimgirawath, Jumrern Laosriratana and Rujee Lorpitthaya
pp. 1209 - 1215
Abstract
The structures previously assigned to (-)-romucosine and (+)-cathafiline, N-(methoxycarbonyl) aporphine alkaloids from Rollina mucosa (Annonaceae) and Cassytha filiformis (Lauraceae) respectively, have been confirmed by total syntheses of the racemic substances. The key step of the syntheses involved formation of ring C of the aporphines by a radical-initiated cyclisation.
