In coastal regions of Bangladesh, sources of irrigation are rain, surface and groundwater. Due to rainfall anomaly and saline contamination, it is important to identify deep groundwater that is eligible for irrigation. The main goal of the study was to identify deep groundwater which is suitable for irrigation. Satkhira Sadar Upazila, at the southwestern coastal zone of Bangladesh, was the study area, which was divided into North, Center and South zones. Twenty samples of groundwater were analyzed for salinity (0.65-4.79 ppt), sodium absorption ratio (1.14-11.62), soluble sodium percentage (32.95-82.21), electrical conductivity (614-2082.11 µS/cm), magnesium adsorption ratio (21.96-26.97), Kelly’s ratio (0.48-4.62), total hardness (150.76-313.33 mg/l), permeability index (68.02-94.16) and residual sodium bi-carbonate (79.68-230.72 mg/l). Chemical constituents and values were compared with national and international standards. Northern deep groundwater has the highest salinity and chemical concentrations. Salinity and other chemical concentrations show a decreasing trend towards the south. Low chemical concentrations in the southern region indicate the best quality groundwater for irrigation