Supinya Tewtrakul, Sanan Subhadhirasakul, and Sopa Kummee

pp. 239 - 243

Abstract

Thirty-six chloroform-, methanol-, and water- extracts of some plants used as self mediciation by
AIDS patients were investigated for their HIV-1 protease (HIV-1 PR) inhibitory activities. Of these extracts,
Boesenbergia pandurata (rhizome, chloroform extract) showed the most potent inhibitory activity against
HIV-1 PR, followed by Boesenbergia pandurata (rhizome, MeOH extract) and Alpinia galanga (rhizome,
MeOH extract) with the inhibitions of 64.92, 51.92 and 48.70%, respectively, at concentration of 100 µg/ml.