Original Article |
2003, Vol.25, No.4, pp. 503-508
HIV-1 protease inhibitory substances from the rhizomes of Boesenbergia pandurata Holtt.
Supinya Tewtrakul, Sanan Subhadhirasakul, Jindaporn Puripattanavong, and Tassanee Panphadung
pp. 503 - 508
Abstract
Four flavonoids (pinostrobin, pinocembrin, cardamonin and alpinetin) isolated from the ethanol extract of Boesenbergia pandurata Holtt. (yellow rhizome) were tested for their activities against HIV-1 protease (HIV-PR). The result showed that cardamonin exhibited an appreciable anti-HIV-1 PR activity with an IC50 value of 31 µg/ml.
