This study investigated the influence of proximal radius fracture pattern on the biomechanical performance of locking compression plate (LCP) using the finite element method. Two transverse neck fracture levels and one oblique proximal radius fracture, stabilized with stainless steel and titanium implants, were included in this study. The models of proximal radius and LCP implant set were created and virtually aligned using CAD. Four-node tetrahedral elements were used in the FE model. Articular contact pressures at the 0º, 45º, and 90º flexion angle of humeroradial ulna joint were applied to articular surface of the proximal radius. High stress concentrations were found between the proximal screws holes and around the combined holes of LCP. Elastic strain at fracture gap stabilized with implant did not significantly differ between stainless steel and titanium implants. The stainless steel implant may present higher stresses than the titanium implant, especially with a fracture close to the articular surface.