As industries worldwide focus on sustainable businesses, it has to be adapted using alternative protein feedstocks in animal feed. Therefore, this research was interested in the zero percent fishmeal diets and supplementing it with trace minerals (TM), compared to 15% of fishmeal diets. The diets were assigned in three treatments; the first treatment is a control group with fishmeal 15%, the second and third are the zero fishmeal diets with supplementing TM 0.12% for adjusted TM level equal to fishmeal 15% (T1) and TM 0.18% for increasing the level of TM in the diet two times of fishmeal 15%. The shrimp (0.6940- 0.7060 g body weight) were fed by each type of experimental diets, and growth and immune parameters were investigated at the end of 4-week trial. The growth, total hemocyte count, superoxide dismutase, and glutathione showed no difference between fishmeal 15% and fishmeal 0% groups (P>0.05), except phenoloxidase activity exhibited a higher response when increasing the TM concentration (P<0.05). These results indicated the potential to reducing fishmeal in the white shrimp diet to zero percent without any adverse effect on growth and immune response based on TM supplementing at the growing state or four weeks.