Original Article |
2006, Vol.28, No.1, pp. 107-114
Effects of Naphthalene on DNA and RNA quantity in Amoeba proteus by using confocal laser scanning microscope
Jiraporn Khwanmuni
pp. 107 - 114
Abstract
Effects of Naphthalene which is a carcinogen on changes of DNA and RNA quantities were studied with acridine orange stained cells under a confocal laser scanning microscope. It was found that DNA and RNA in amoebae nucleus and cytoplasm, reared in 0 (control), 3 and 8.85 mg/l (24h-LD50) at 0 and 12 h. showed a statistically significant difference (p<0.05). The more naphthalene concentrations and larger incubation periods had greater effects on DNA and RNA decreases in amoebae nucleus and cytoplasm.